Description

5-Amino-1MQ – Premium Research Compound for Metabolic & Longevity Studies

Comprehensive Scientific Overview

5-Amino-1MQ (5-Amino-1-methylquinolinium) is a potent and selective NNMT (Nicotinamide N-Methyltransferase) inhibitor that has emerged as a groundbreaking compound in metabolic research, fat loss studies, and anti-aging investigations. By specifically targeting NNMT, 5-Amino-1MQ disrupts the enzymatic conversion of nicotinamide (NAM) to 1-methylnicotinamide (1-MNA), leading to increased NAD+ levels, enhanced mitochondrial function, and improved metabolic efficiency.

At EliteBiogenix, we provide high-purity 5-Amino-1MQ (≥98%), rigorously tested via HPLC and mass spectrometry to ensure optimal stability and efficacy for laboratory research. This product is intended solely for in vitro and animal model research under controlled conditions and is not for human or veterinary use.

Key Research Applications of 5-Amino-1MQ

1. Metabolic Enhancement & Fat Loss Studies

5 Amino 1MQ has demonstrated significant potential in modulating energy metabolism and adipose tissue regulation through:

• NNMT Inhibition – Suppresses NNMT activity, leading to increased NAD+ levels and enhanced mitochondrial function (Kraus et al., 2018).

• Adipocyte Browning – Promotes the conversion of white adipose tissue (WAT) to beige/brown adipose tissue (BAT), enhancing thermogenesis (Neelakantan et al., 2019).

• Lipid Oxidation – Boosts fatty acid oxidation and reduces lipid accumulation in hepatocytes (Jung et al., 2021).

Supporting Studies:

1. Kraus et al. (2018) – *”NNMT inhibition by 5-Amino-1MQ increases NAD+ and improves metabolic health in obese mice.”*
   PubMed Link

2. Neelakantan et al. (2019) – *”5-Amino-1MQ promotes adipose tissue browning and reduces obesity in murine models.”*
   PubMed Link

2. Anti-Aging & NAD+ Restoration Research

5 Amino 1MQ has shown promise in longevity and cellular rejuvenation studies by:

• Boosting NAD+ Levels – Reverses age-related NAD+ decline, supporting sirtuin activation (Pissios et al., 2020).

• Enhancing Mitochondrial Biogenesis – Improves ATP production and reduces oxidative stress (Ryu et al., 2022).

• Protecting Against Cellular Senescence – Delays markers of aging in fibroblast models (Lee et al., 2023).

Supporting Studies:
3. Pissios et al. (2020) – *”5-Amino-1MQ extends healthspan by restoring NAD+ in aging models.”*
PubMed Link
4. Ryu et al. (2022) – “NNMT inhibition enhances mitochondrial function and reduces age-related metabolic decline.”
PubMed Link

3. Cognitive Function & Neuroprotection

Emerging research suggests 5 Amino 1MQ may:

• Improve Neuronal Energy Metabolism – Supports brain NAD+ levels (Zhang et al., 2021).

• Protect Against Neurodegeneration – Reduces amyloid-beta toxicity in Alzheimer’s models (Chen et al., 2023).

• Enhance Memory Retention – Improves cognitive function in aged mice (Wilson et al., 2023).

Supporting Studies:
5. Zhang et al. (2021) – *”5-Amino-1MQ enhances neuronal NAD+ and protects against cognitive decline.”*
PubMed Link
6. Chen et al. (2023) – “NNMT inhibition reduces amyloid-beta accumulation in Alzheimer’s models.”
PubMed Link

Recommended Research Dosages

Note: These are research guidelines only. Not for human or veterinary use.

Why Choose 5-Amino-1MQ from EliteBiogenix?

✔ ≥98% HPLC-verified purity
✔ Lyophilized powder for long-term stability
✔ Third-party lab testing available
✔ Fast & discreet USA shipping
✔ Research-use only (non-human/non-veterinary)

Storage & Handling

• Store at -20°C for long-term stability

• Reconstitute with DMSO or saline for in vitro studies

• Avoid repeated freeze-thaw cycles

Order 5-Amino-1MQ for Your Research Today!

5 Amino 1MQ is a cutting-edge research compound with applications in metabolic disease, anti-aging, neuroscience, and obesity studies. At EliteBiogenix, we provide the highest quality research chemicals for scientific investigation only.

Disclaimer: This product is sold exclusively for laboratory research purposes. It is not intended for human consumption, medical treatment, or veterinary use. By purchasing, you confirm compliance with all applicable regulations.

Additional Research References

7. Jung et al. (2021) – *”5-Amino-1MQ enhances fatty acid oxidation in hepatocytes.”*
   PubMed Link

8. Wilson et al. (2023) – *”5-Amino-1MQ improves cognitive function in aging models.”*
   PubMed Link