Description

MK677 Cardarine Research Stack from EliteBiogenix – Premium Research Compounds for Metabolic & Longevity Studies

1 MK677 30m

1 Cardarine 30ml

Introduction to the MK677 Cardarine Research Stack

The MK677 Cardarine Research Stack represents a cutting-edge combination for researchers studying metabolic regulation, muscle preservation, and endurance enhancement in preclinical models. This synergistic pairing leverages:

✔ MK677 – A growth hormone secretagogue that stimulates IGF-1 production without peptide hormones.
✔ Cardarine – A PPARδ agonist that enhances fat oxidation and exercise capacity in research models.

At EliteBiogenix.com, we provide ≥98% pure, analytically verified MK-677 & Cardarine strictly for scientific investigation. These compounds are not for human or veterinary use and are intended solely for controlled laboratory studies exploring:

• Muscle atrophy prevention (MK-677)

• Endurance and metabolic efficiency (Cardarine)

• Age-related growth hormone decline

• PPARδ-mediated lipid metabolism

Why Researchers Choose The MK677 Cardarine Research Stack

1. MK677 (Ibutamoren) – Growth Hormone Research Applications

• MK677 Cardarine Research Stack Mechanism: Ghrelin receptor agonist → increases GH & IGF-1 secretion

• Key Study Areas:

  • Sarcopenia (muscle wasting) models

  • Bone density and recovery studies

  • Sleep architecture and REM cycle research

• Dosing in Models:

  • Murine studies: 1-5 mg/kg/day (oral)

  • In vitro assays: 10-100 nM concentration

2. Cardarine (GW-501516) – PPARδ Metabolic Activator

• MK677 Cardarine Research Stack Mechanism: PPARδ agonism → up-regulates fatty acid oxidation

• Key Study Areas:

  • Endurance performance in rodent models

  • Obesity and metabolic syndrome research

  • Glucose uptake and insulin sensitivity

• Dosing in Models:

  • Murine studies: 2-10 mg/kg/day (oral)

  • Cell culture: 1-10 μM for metabolic assays

3. Synergistic Research Benefits of the MK677 Cardarine Research Stack

• MK-677 → Preserves lean mass in catabolic states

• Cardarine → Enhances lipid utilization for energy

• Combined Effect: Ideal for muscle endurance & metabolic efficiency studies

EliteBiogenix Quality Assurance

✅ ≥98% Purity (HPLC-verified)
✅ Batch-specific Certificates of Analysis (COA)
✅ Non-GMO, solvent-free synthesis
✅ Stable lyophilized (MK-677) & liquid (Cardarine) formulations

Research Protocol Guidelines

1. MK677 Cardarine Research Stack In Vitro Applications

• MK-677: Study GH secretion in pituitary cell lines (10-100 nM)

• Cardarine: PPARδ activation assays (1-10 μM in hepatocytes)

2. MK677 Cardarine Research Stack Murine Model Administration

3. MK677 Cardarine Research Stack Storage & Stability

• MK-677: Store at -20°C (long-term), 4°C (short-term)

• Cardarine: Stable at room temp (avoid light/heat)

Safety & Compliance

⚠ For research use only – Not for human/animal consumption
⚠ Requires IACUC approval for vertebrate studies
⚠ PPE required (gloves, lab coat)

Regulatory Status:

• Not FDA-approved for any application

• Complies with 21 CFR §210/211 (cGMP)

Order EliteBiogenix MK677 Cardarine Research Stack

Catalog #: EBX-MKGW-STK
Form: MK-677 (lyophilized), Cardarine (solution)
Purity: ≥98% (each)
Storage: -20°C (MK-677), RT (Cardarine)

MK-677 & Cardarine Stack Study & References:

Key Findings from MK677 Studies

1. Growth Hormone Release: Research shows that MK-677 significantly increases IGF-1 and IGF-binding protein-3 (IGFBP-3) levels, making it a promising option for addressing growth hormone deficiencies and supporting muscle growth.
2. Body Composition: Clinical trials have found that MK-677 improves bone mineral density, muscle mass, and overall body composition in older adults. A randomized controlled trial also noted enhanced nitrogen retention, even during calorie restriction, suggesting its potential for preserving muscle mass in challenging conditions.
3. Sleep Quality: Studies indicate that MK-677 improves REM sleep duration and reduces REM latency, particularly in older adults. Enhanced stage 4 sleep, crucial for tissue repair, further highlights its potential for recovery and neurological health.
4. Chronic Disease Potential: Animal studies suggest that MK-677 may reduce neuroinflammation, neurodegeneration, and beta-amyloid buildup, offering potential preventive benefits against conditions like Alzheimer’s disease. However, more human studies are needed to confirm these findings.

References:

1. Oral administration of MK677 increases markers of bone turnover in elderly adults. PubMed
2. Design and biological activities of MK677. PubMed
3. MK-677 stimulates the GH/IGF-1 axis in GH-deficient adults. Journal of Clinical Endocrinology & Metabolism
4. MK-677 improves sleep quality in humans. PubMed
5. MK-677 reverses diet-induced catabolism. PubMed
6. MK-677 alleviates amyloid-beta pathology in Alzheimer’s models. PubMed

Cardarine Research Findings

Numerous animal studies highlight Cardarine’s potential to improve energy metabolism and blood lipid profiles:

• A study on mice demonstrated that GW501516 enhances fatty acid oxidation and alleviates metabolic syndrome [1].
• Research on Kunming mice showed that PPAR activation significantly boosts running endurance [2].
• Another study found that PPARs prevent glucose depletion during exercise, delaying fatigue [3].
• In obese rhesus monkeys, GW501516 increased HDL and reduced VLDL, suggesting cardioprotective effects [6].
• Phase II clinical trials indicated Cardarine’s potential benefits for obesity, diabetes, dyslipidemia, and cardiovascular health, along with reduced inflammation [7, 8].
• A study on high-fructose-fed rats found that GW501516 lowered inflammation markers and upregulated genes involved in beta-oxidation [11].

MK677 Cardarine Research Stack References:

• PPARδ-Mediated Fat Oxidation (PNAS, 2003)

• Endurance Capacity Models (Scientific Reports, 2015)

• Glucose Preservation (Cell Metabolism, 2017)

• Cardarine induces fatty acid β-oxidation (Tanaka et al., PNAS 2003)

• Enhances running endurance in murine models (Chen et al., Sci Rep 2015)

• Promotes reverse cholesterol transport (Oliver et al., PNAS 2001)

• Improves inflammatory states in metabolic syndrome (Magliano et al., Endocrine 2015)

Why EliteBiogenix?

✅ IRB/IACUC documentation support
✅ Bulk quantities for institutions
✅ Discreet shipping to US labs

Disclaimer: This product is for research purposes only.

Advance your metabolic research today with the MK677 Cardarine Research Stack at EliteBiogenix!